The Interact direction is ˇ°Entity1ˇ± to ˇ°Entity2ˇ±, when it exists. The mark * is used to separate the members of complex. The mark # is used to separate the members of family. The mark ~ is used to separate the members of complex family. ˇ°ReferenceIDˇ± mainly contain PubMed ID, and some with doi number. "Effect" is with 3 status: Activation (A), Inhibition (I) and Unspecified (U). ˇ°Modificationˇ± abbreviations list below: Acetylation/Deacetylation Ac+/Ac- Biotinylation/Debiotinylation Biotin+/Biotin- Decanoylation/Dedecanoylation Decanoyl+/Decanoyl- Dimethylation/Dedimethylation Me2+/Me2- Farnesylation/Defarnesylation Farnesyl+/Farnesyl- Fucosylation/Defucosylation Fucosyl+/Fucosyl- Galactosylation/Degalactosylation Gal+/Gal- Geranylgeranylation/Degeranylgeranylation GG+/GG- Glucosylation/Deglucosylation Glucosyl+/Glucosyl- Glycosylation/Deglycosylation Glycosyl+/Glycosyl- Glycylation/Deglycylation Glycyl+/Glycyl- Hydroxylation/Dehydroxylation Hydroxyl+/Hydroxyl- Lipoylation/Delipoylation Lipoyl+/Lipoyl- Methylation/Demethylation Me+/Me- Myristoylation/Demyristoylation Myristoyl+/Myristoyl- Octanoylation/Deoctanoylation Octanoyl+/Octanoyl- Palmitoylation/Depalmitoylation Palmitoyl+/Palmitoyl- Phosphopantetheine/Dephosphopantetheine Phosphopantetheine+/Phosphopantetheine- Phosphorylation/Dephosphorylation Phos+/Phos- Sumoylation/Desumoylation Sumo+/Sumo- Trimethylation/Detrimethylation Me3+/Me3- Ubiquitination/Deubiquitination Ub+/Ub- PathPPI v1.0 (2013.11.16) contains: PID (contains only the data curated by PID, version 2012.03.17) BioCarta (from PID, version 2010.08.11) Reactome (version 2012.03.14) NetPath (downloaded 2012.04.14) INOH (version 2011.01.31) SPIKE (version 2011.03.22 KEGG (downloaded 2009.10.12) HPRD (version R9) IntAct (downloaded 2013.10.22) BioGRID (version 3.2.105) MINT (version 2013.03.26) DIP (version 2013.07.07)